Definition of "Plague" :

noun: an annoyance

"Those children are a damn plague."

noun: any large scale calamity (especially when thought to be sent by God)

noun: a swarm of insects that attack plants

"A plague of grasshoppers."

noun: any epidemic disease with a high death rate

noun: a serious (sometimes fatal) infection of rodents caused by Yersinia pestis and accidentally transmitted to humans by the bite of a flea that has bitten an infected animal

verb: annoy continually or chronically

verb: cause to suffer a blight